Three Dimensional Asymmetric Microenvironment for Cell Biological Studies

STAT3 as a Key Factor in Tumor Microenvironment and Cancer Stem Cell

Background Recent studies revealed that tumor-associated macrophages (TAMs) play a decisive role in the regulation of tumor progression by manipulating tumor oncogenesis, angiogenesis and immune functions within tumor microenvironments. Signal transducer and activator of transcription 3 (STAT3), which is a point of convergence for numerous oncogenic signalling pathways, is constitutively activ...

Tissue Engineered Scaffolds in Regenerative Medicine

Stem cells are self-renewing cells that can be differentiated into other cell types. Conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2D) cultures. The design of three-dimensional (3D) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissu...

Dynamic Analysis of Three Dimensional Asymmetric Isolated Structures

Dynamic Analysis of Three Dimensional Asymmetric Isolated Structures

A Novel Toolbox for Generating Realistic Biological Cell Geometries for Electromagnetic Microdosimetry

Researchers in bioelectromagnetics often require realistic tissue, cellular and sub-cellular geometry models for their simulations. However, biological shapes are often extremely irregular, while conventional geometrical modeling tools on the market cannot meet the demand for fast and efficient construction of irregular geometries. We have designed a free, user-friendly tool in MATLAB that comb...